研究業績

2026年

学術論文

• "An Ordinary Differential Equation-Based Integrated Pharmacokinetic–Pharmacodynamic Model for Predicting Anticoagulant Responses to Warfarin and Diphacinone Across Rodent and Bat Species"
  Misaki Fukamatsu, Moyu Miyamae, Ryo Kamata, Kazuki Takeda
  The Journal of Veterinary Medical Science In Press (2026).
• "Isomer-Dependent Pharmacokinetic Behavior and VKOR Interactions of Second-Generation Anticoagulant Rodenticides: An Integrated In Vivo–In Vitro–In Silico Investigation"
  Moyu Miyamae, Satoru Nagaoka, Teppei Hayama, Misaki Fukamatsu, Ryo Kamata, Kazuki Takeda
  International Journal of Molecular Sciences 27, 9, 3794 (2026).

  • DOI: https://doi.org/10.3390/ijms27093794
• "Perfluorohexanesulfonic acid-induced inhibition of human palate cell proliferation through upregulation of miR-374a-5p"
  Hiroki YOSHIOKA, Hanane HORITA, Kenichi OGATA, Kazuki TAKEDA, Hyogo HORIGUCHI, Yosuke TSUKIBOSHI
  Biomedical Research 47, 1, 1 - 10 (2026).

  • DOI: https://doi.org/10.2220/biomedres.47.1

国内学会発表

• "ヒト全タンパク質への網羅的分子ドッキングによる ビタミンK新規標的候補の探索"
  羽山哲平 , 鎌田亮 , 武田一貴
  第8回 日本獣医薬理学・毒性学会・春季研究会 (2026).
• "麦角アルカロイドとモノアミン受容体のin silico相互作用解析"
  辰田鴻志郎, 羽山哲平, 鎌田亮, 武田一貴
  第8回 日本獣医薬理学・毒性学会・春季研究会 (2026).
• "AlphaFoldを活用したエストロゲン受容体アゴニスト/アンタゴニスト結合型構造予測"
  北岡優希, 中村友香, 羽山哲平, 鎌田亮, 武田一貴
  第8回 日本獣医薬理学・毒性学会・春季研究会 (2026).

国際学会発表

• "Binding-Proteomics in the AlphaFold Era: Scalable Proteome-Wide Docking for Mechanistic Toxicology and Cross-Species Risk Assessment."
  Kazuki Takeda
  SOT 65th Annual Meeting (2026).

  INVITED "Global Session: Structure-Based Toxicology in the AlphaFold Era: Emerging Opportunities and Unmet Challenges"